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Estimating uncertainty in predicted folding free energy changes of RNA secondary structures

Nearest neighbor parameters for estimating the folding stability of RNA are commonly used in secondary structure prediction, for generating folding ensembles of structures, and for analyzing RNA function. Previously, we demonstrated that we could quantify the uncertainties in each nearest neighbor p...

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Detalles Bibliográficos
Autores principales: Zuber, Jeffrey, Mathews, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521603/
https://www.ncbi.nlm.nih.gov/pubmed/30952689
http://dx.doi.org/10.1261/rna.069203.118