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Estimating uncertainty in predicted folding free energy changes of RNA secondary structures
Nearest neighbor parameters for estimating the folding stability of RNA are commonly used in secondary structure prediction, for generating folding ensembles of structures, and for analyzing RNA function. Previously, we demonstrated that we could quantify the uncertainties in each nearest neighbor p...
Autores principales: | Zuber, Jeffrey, Mathews, David H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521603/ https://www.ncbi.nlm.nih.gov/pubmed/30952689 http://dx.doi.org/10.1261/rna.069203.118 |
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