Cargando…

Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis

Eukaryotic ribosome biogenesis is a highly orchestrated process involving numerous assembly factors including ATP-dependent RNA helicases. The DEAH helicase DHX37 (Dhr1 in yeast) is activated by the ribosome biogenesis factor UTP14A to facilitate maturation of the small ribosomal subunit. We report...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boneberg, Franziska M., Brandmann, Tobias, Kobel, Lena, van den Heuvel, Jasmin, Bargsten, Katja, Bammert, Lukas, Kutay, Ulrike, Jinek, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521606/ https://www.ncbi.nlm.nih.gov/pubmed/30910870 http://dx.doi.org/10.1261/rna.069609.118

Ejemplares similares

The ribosome biogenesis factor yUtp23/hUTP23 coordinates key interactions in the yeast and human pre-40S particle and hUTP23 contains an essential PIN domain
por: Wells, Graeme R., et al.
Publicado: (2017)

The human RNA helicase DHX37 is required for release of the U3 snoRNP from pre-ribosomal particles
por: Choudhury, Priyanka, et al.
Publicado: (2018)

The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis
por: Freed, Emily F., et al.
Publicado: (2010)

Structural basis for 5'-ETS recognition by Utp4 at the early stages of ribosome biogenesis
por: Calviño, Fabiola R., et al.
Publicado: (2017)

Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3′ end biogenesis
por: Muckenfuss, Lena Maria, et al.
Publicado: (2022)

Ribosome biogenesis factors—from names to functions
por: Dörner, Kerstin, et al.
Publicado: (2023)

Regulation of Sli15/INCENP, kinetochore, and Cdc14 phosphatase functions by the ribosome biogenesis protein Utp7
por: Jwa, Miri, et al.
Publicado: (2008)

The G-patch protein NF-κB-repressing factor mediates the recruitment of the exonuclease XRN2 and activation of the RNA helicase DHX15 in human ribosome biogenesis
por: Memet, Indira, et al.
Publicado: (2017)

UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly
por: Hunziker, Mirjam, et al.
Publicado: (2016)

Human AATF/Che-1 forms a nucleolar protein complex with NGDN and NOL10 required for 40S ribosomal subunit synthesis
por: Bammert, Lukas, et al.
Publicado: (2016)

RNA folding and functions of RNA helicases in ribosome biogenesis
por: Mitterer, Valentin, et al.
Publicado: (2022)

The Ribosomal Biogenesis Protein Utp21 Interacts with Hsp90 and Has Differing Requirements for Hsp90-Associated Proteins
por: Tenge, Victoria R., et al.
Publicado: (2014)

Crystal structure of the C‐terminal 2′,5′‐phosphodiesterase domain of group a rotavirus protein VP3
por: Brandmann, Tobias, et al.
Publicado: (2015)

The enigmatic helicase DHX9 and its association with the hallmarks of cancer
por: Gulliver, Chloe, et al.
Publicado: (2020)

Structure and RNA recognition of ribosome assembly factor Utp30
por: Hu, Jianfei, et al.
Publicado: (2017)

RNA helicase DHX15 acts as a tumour suppressor in glioma
por: Ito, Shingo, et al.
Publicado: (2017)

DNA/RNA helicase DHX36 is required for late stages of spermatogenesis
por: Zhang, Kejia, et al.
Publicado: (2022)

Crystal structures of the DExH-box RNA helicase DHX9
por: Lee, Young-Tae, et al.
Publicado: (2023)

RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1
por: Liu, Zhen, et al.
Publicado: (2022)

WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase
por: Chakraborty, Prasun, et al.
Publicado: (2010)

Tumor Cell Survival Dependence on the DHX9 DExH-Box Helicase
por: Lee, Teresa, et al.
Publicado: (2016)

G-Quadruplexes and the DNA/RNA helicase DHX36 in health, disease, and aging
por: Antcliff, Aaron, et al.
Publicado: (2021)

RNA helicase DHX15 exemplifies a unique dependency in acute leukemia
por: Guo, Hao, et al.
Publicado: (2023)

Structural and functional analysis of Utp24, an endonuclease for processing 18S ribosomal RNA
por: An, Weidong, et al.
Publicado: (2018)

At least two molecules of the RNA helicase Has1 are simultaneously present in pre-ribosomes during ribosome biogenesis
por: Gnanasundram, Sivakumar Vadivel, et al.
Publicado: (2019)

In Vitro Reconstitution of Yeast tUTP/UTP A and UTP B Subcomplexes Provides New Insights into Their Modular Architecture
por: Pöll, Gisela, et al.
Publicado: (2014)

Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome
por: McElreavey, Ken, et al.
Publicado: (2019)

The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans
por: Wells, Graeme R., et al.
Publicado: (2016)

The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans
por: Wells, Graeme R., et al.
Publicado: (2016)

Integrative Expression and Prognosis Analysis of DHX37 in Human Cancers by Data Mining
por: Huang, Kang, et al.
Publicado: (2021)

Up-regulation and clinical relevance of novel helicase homologue DHX32 in colorectal cancer
por: Huang, Chunling, et al.
Publicado: (2009)

The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1
por: Booy, Evan P., et al.
Publicado: (2014)

DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing
por: Chakraborty, Prasun, et al.
Publicado: (2018)

Dependence of p53-deficient cells on the DHX9 DExH-box helicase
por: Lee, Teresa, et al.
Publicado: (2017)

Targeting RNA helicase DHX33 blocks Ras‐driven lung tumorigenesis in vivo
por: Wang, Xingshun, et al.
Publicado: (2020)

Prp43/DHX15 exemplify RNA helicase multifunctionality in the gene expression network
por: Bohnsack, Katherine E, et al.
Publicado: (2022)

Synergistic interaction network between the snR30 RNP, Utp23, and ribosomal RNA during ribosome synthesis
por: Vos, Timothy J., et al.
Publicado: (2022)

Function of Plant DExD/H-Box RNA Helicases Associated with Ribosomal RNA Biogenesis
por: Liu, Yuelin, et al.
Publicado: (2018)

DHX37 Impacts Prognosis of Hepatocellular Carcinoma and Lung Adenocarcinoma through Immune Infiltration
por: Xu, Yanni, et al.
Publicado: (2020)

The DNA/RNA helicase DHX9 contributes to the transcriptional program of the androgen receptor in prostate cancer
por: Chellini, Lidia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vth6ivrmkq0nn99oqhvr7jjm95