Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria

BACKGROUND: The present study was conducted to determine antimicotic susceptibility of Candida species (sp.) from patients with symptomatic candiduria. MATERIALS AND METHODS: Identification of Candida sp. and determination of efficacy of most routine antifungals were done using polymerase chain reac...

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Autores principales: Barati, Mitra, Mirkalantari, Shiva, Ansari, Saham, Salari, Samira, Fattahi, Azam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521611/
https://www.ncbi.nlm.nih.gov/pubmed/31143236
http://dx.doi.org/10.4103/jrms.JRMS_880_18
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author Barati, Mitra
Mirkalantari, Shiva
Ansari, Saham
Salari, Samira
Fattahi, Azam
author_facet Barati, Mitra
Mirkalantari, Shiva
Ansari, Saham
Salari, Samira
Fattahi, Azam
author_sort Barati, Mitra
collection PubMed
description BACKGROUND: The present study was conducted to determine antimicotic susceptibility of Candida species (sp.) from patients with symptomatic candiduria. MATERIALS AND METHODS: Identification of Candida sp. and determination of efficacy of most routine antifungals were done using polymerase chain reaction-restriction fragment length polymorphism method and E-test, respectively. RESULTS: The results from susceptibility test reveal that caspofungin and amphotericin B have high antifungal activity against both albicans (100% and 96%, respectively) and nonalbicans (95.11% and 72.72%, respectively) isolates. CONCLUSION: The present study suggests that caspofungin and amphotericin B have the excellent ability to eradicate both Candida groups that showed decreased susceptibility to other compounds.
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spelling pubmed-65216112019-05-29 Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria Barati, Mitra Mirkalantari, Shiva Ansari, Saham Salari, Samira Fattahi, Azam J Res Med Sci Short Communication BACKGROUND: The present study was conducted to determine antimicotic susceptibility of Candida species (sp.) from patients with symptomatic candiduria. MATERIALS AND METHODS: Identification of Candida sp. and determination of efficacy of most routine antifungals were done using polymerase chain reaction-restriction fragment length polymorphism method and E-test, respectively. RESULTS: The results from susceptibility test reveal that caspofungin and amphotericin B have high antifungal activity against both albicans (100% and 96%, respectively) and nonalbicans (95.11% and 72.72%, respectively) isolates. CONCLUSION: The present study suggests that caspofungin and amphotericin B have the excellent ability to eradicate both Candida groups that showed decreased susceptibility to other compounds. Wolters Kluwer - Medknow 2019-04-26 /pmc/articles/PMC6521611/ /pubmed/31143236 http://dx.doi.org/10.4103/jrms.JRMS_880_18 Text en Copyright: © 2019 Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Short Communication
Barati, Mitra
Mirkalantari, Shiva
Ansari, Saham
Salari, Samira
Fattahi, Azam
Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria
title Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria
title_full Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria
title_fullStr Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria
title_full_unstemmed Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria
title_short Determination of antimicotic susceptibility pattern of Candida species isolated from patients with symptomatic candiduria
title_sort determination of antimicotic susceptibility pattern of candida species isolated from patients with symptomatic candiduria
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521611/
https://www.ncbi.nlm.nih.gov/pubmed/31143236
http://dx.doi.org/10.4103/jrms.JRMS_880_18
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