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Impaired Reversal Learning in APPPS1-21 Mice in the Touchscreen Visual Discrimination Task
Preclinical-clinical translation of cognitive functions has been difficult in Alzheimer’s disease (AD) research but is crucial to the (predictive) validity of AD animal models. Reversal learning, a representation of flexibility and adaptability to a changing environment, might represent such a trans...
Autores principales: | Van den Broeck, Lore, Hansquine, Pierre, Callaerts-Vegh, Zsuzsanna, D’Hooge, Rudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521801/ https://www.ncbi.nlm.nih.gov/pubmed/31143103 http://dx.doi.org/10.3389/fnbeh.2019.00092 |
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