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Impaired Reversal Learning in APPPS1-21 Mice in the Touchscreen Visual Discrimination Task

Preclinical-clinical translation of cognitive functions has been difficult in Alzheimer’s disease (AD) research but is crucial to the (predictive) validity of AD animal models. Reversal learning, a representation of flexibility and adaptability to a changing environment, might represent such a trans...

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Detalles Bibliográficos
Autores principales: Van den Broeck, Lore, Hansquine, Pierre, Callaerts-Vegh, Zsuzsanna, D’Hooge, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521801/
https://www.ncbi.nlm.nih.gov/pubmed/31143103
http://dx.doi.org/10.3389/fnbeh.2019.00092

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