Cargando…
The ER Membrane Protein Complex Promotes Biogenesis of Dengue and Zika Virus Non-structural Multi-pass Transmembrane Proteins to Support Infection
Although flaviviruses co-opt the function of the host endoplasmic reticulum (ER) membrane protein complex (EMC) during infection, a mechanistic explanation for this observation remains unclear. Here, we show that the EMC promotes biogenesis of dengue virus (DENV) and Zika virus (ZIKV) non-structural...
Autores principales: | Lin, David L., Inoue, Takamasa, Chen, Yu-Jie, Chang, Aaron, Tsai, Billy, Tai, Andrew W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521869/ https://www.ncbi.nlm.nih.gov/pubmed/31067454 http://dx.doi.org/10.1016/j.celrep.2019.04.051 |
Ejemplares similares
-
An ER translocon for multi-pass membrane protein biogenesis
por: McGilvray, Philip T, et al.
Publicado: (2020) -
Regulated Erlin-dependent release of the B12 transmembrane J-protein promotes ER membrane penetration of a non-enveloped virus
por: Inoue, Takamasa, et al.
Publicado: (2017) -
Ribosomal stalk proteins RPLP1 and RPLP2 promote biogenesis of flaviviral and cellular multi-pass transmembrane proteins
por: Campos, Rafael K, et al.
Publicado: (2020) -
Visualization of translation and protein biogenesis at the ER membrane
por: Gemmer, Max, et al.
Publicado: (2023) -
The ER membrane protein complex is a transmembrane domain insertase
por: Guna, Alina, et al.
Publicado: (2017)