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Mice lacking EFA6C/Psd2, a guanine nucleotide exchange factor for Arf6, exhibit lower Purkinje cell synaptic density but normal cerebellar motor functions

ADP ribosylation factor 6 (Arf6) is a small GTPase that regulates various neuronal events including formation of the axon, dendrites and dendritic spines, and synaptic plasticity through actin cytoskeleton remodeling and endosomal trafficking. EFA6C, also known as Psd2, is a guanine nucleotide excha...

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Detalles Bibliográficos
Autores principales: Saegusa, Shintaro, Fukaya, Masahiro, Kakegawa, Wataru, Tanaka, Manabu, Katsumata, Osamu, Sugawara, Takeyuki, Hara, Yoshinobu, Itakura, Makoto, Okubo, Tadashi, Sato, Toshiya, Yuzaki, Michisuke, Sakagami, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522047/
https://www.ncbi.nlm.nih.gov/pubmed/31095630
http://dx.doi.org/10.1371/journal.pone.0216960