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A multicentre retrospective cohort study of ovarian germ cell tumours: Evidence for chemotherapy de-escalation and alignment of paediatric and adult practice

BACKGROUND: Adult guidelines recommend BEP (bleomycin, etoposide, cisplatin) for all ovarian germ cell tumours, causing debilitating toxicities in young patients who will survive long term. Paediatricians successfully reduce toxicities by using lower bleomycin doses and substituting carboplatin for...

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Detalles Bibliográficos
Autores principales: Newton, C., Murali, K., Ahmad, A., Hockings, H., Graham, R., Liberale, V., Sarker, S.-J., Ledermann, J., Berney, D.M., Shamash, J., Banerjee, S., Stoneham, S., Lockley, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522056/
https://www.ncbi.nlm.nih.gov/pubmed/30954883
http://dx.doi.org/10.1016/j.ejca.2019.03.001