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Analysis of PK11195 concentrations in rodent whole blood and tissue samples by rapid and reproducible chromatographic method to support target-occupancy PET studies

In Positron Emission Tomography (PET) research, it is important to assess not only pharmacokinetics of a radiotracer in vivo, but also of the drugs used in blocking/displacement PET studies. Typically, pharmacokinetic/pharmacodynamic (PK/PD) analyses of drugs used in rodent PET studies are based on...

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Detalles Bibliográficos
Autores principales:	Stadulytė, Agnė, Alcaide-Corral, Carlos José, Walton, Tashfeen, Lucatelli, Christophe, Tavares, Adriana Alexandre S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522057/ https://www.ncbi.nlm.nih.gov/pubmed/31005772 http://dx.doi.org/10.1016/j.jchromb.2019.04.026

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