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Tracking and clarifying differential traits of classical- and atypical L-type bovine spongiform encephalopathy prions after transmission from cattle to cynomolgus monkeys
Classical- (C-) and atypical L-type bovine spongiform encephalopathy (BSE) prions cause different pathological phenotypes in cattle brains, and the disease-associated forms of each prion protein (PrPSc) has a dissimilar biochemical signature. Bovine C-BSE prions are the causative agent of variant Cr...
Autores principales: | Hagiwara, Ken’ichi, Sato, Yuko, Yamakawa, Yoshio, Hara, Hideyuki, Tobiume, Minoru, Okemoto-Nakamura, Yuko, Sata, Tetsutaro, Horiuchi, Motohiro, Shibata, Hiroaki, Ono, Fumiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522098/ https://www.ncbi.nlm.nih.gov/pubmed/31095605 http://dx.doi.org/10.1371/journal.pone.0216807 |
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