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Outpatient minor oral surgery in patients with hemophilia: A case series of 23 patients

Hemophilia is an inherited coagulation disorder characterized by deficiency of the coagulation factor VIII or IX. When the management of hemostasis is inadequate, these patients are at high risk of experiencing intra and postoperative bleedings after tooth extractions. Coagulation factor replacement...

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Detalles Bibliográficos
Autores principales: Ramos, Emilio A., Diamante, Maximiliano, Caruso, Diego, Muiño, Juan M., Baques, Alejandra, Antonelli, Ludmila B., Gutierrez, Josefina, Minigutti, Marcelo O., Guerrero, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522108/
https://www.ncbi.nlm.nih.gov/pubmed/31110621
http://dx.doi.org/10.4317/jced.55506
Descripción
Sumario:Hemophilia is an inherited coagulation disorder characterized by deficiency of the coagulation factor VIII or IX. When the management of hemostasis is inadequate, these patients are at high risk of experiencing intra and postoperative bleedings after tooth extractions. Coagulation factor replacement therapy allows performing most surgical procedures safely, although the factor levels and length of treatment have not been clearly determined. In this study, we present our experience in a retrospective series of 112 ambulatory tooth extractions under local anesthesia in 23 patients with hemophilia using a coagulation factor replacement therapy in combination with tranexamic acid. The results obtained with this protocol were satisfactory and only one episode of mild postoperative bleeding occurred after seven days in a patient who did not have good treatment compliance. Key words:Hemophilia, factor replacement therapy, tooth extractions, postoperative complications.