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RB constrains lineage fidelity and multiple stages of tumour progression and metastasis

Mutations in the Retinoblastoma (RB) tumour suppressor pathway are a hallmark of cancer and a prevalent feature of lung adenocarcinoma(1,2,3). Despite being the first tumour suppressor to be identified, the molecular and cellular basis underlying selection for persistent RB loss in cancer remains un...

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Detalles Bibliográficos
Autores principales:	Walter, David M., Yates, Travis J., Ruiz-Torres, Miguel, Kim-Kiselak, Caroline, Gudiel, A. Andrea, Deshpande, Charuhas, Wang, Walter Z., Cicchini, Michelle, Stokes, Kate L., Tobias, John W., Buza, Elizabeth, Feldser, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522292/ https://www.ncbi.nlm.nih.gov/pubmed/31043741 http://dx.doi.org/10.1038/s41586-019-1172-9

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