Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the “Target Sign”

We herein report the case of a 60-year-old man with a “target sign” in the left frontal lobe on magnetic resonance imaging (MRI), which is thought to be a specific sign of cerebral toxoplasmosis. (18)F-fluorodeoxyglucose-positron emission tomography showed no increased uptake, and (201)Tl-single pho...

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Detalles Bibliográficos
Autores principales: Ueno, Hiroki, Norose, Kazumi, Kamimura, Teppei, Mihara, Keichiro, Yamasaki, Fumiyuki, Hikosaka, Kenji, J. Amatya, Vishwa, Takeshima, Yukio, Kurisu, Kaoru, Maruyama, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522404/
https://www.ncbi.nlm.nih.gov/pubmed/30568116
http://dx.doi.org/10.2169/internalmedicine.1156-18
Descripción
Sumario:We herein report the case of a 60-year-old man with a “target sign” in the left frontal lobe on magnetic resonance imaging (MRI), which is thought to be a specific sign of cerebral toxoplasmosis. (18)F-fluorodeoxyglucose-positron emission tomography showed no increased uptake, and (201)Tl-single photon emission computed tomography showed the focal uptake in the left frontal lesion. On a brain biopsy, the patient was given a definitive diagnosis of brain metastasis from diffuse large B-cell lymphoma, and cerebral toxoplasmosis was excluded. In the present case, multilayer intensities on MRI may reflect the fast-growing nature of this tumor.

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