Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the “Target Sign”

We herein report the case of a 60-year-old man with a “target sign” in the left frontal lobe on magnetic resonance imaging (MRI), which is thought to be a specific sign of cerebral toxoplasmosis. (18)F-fluorodeoxyglucose-positron emission tomography showed no increased uptake, and (201)Tl-single pho...

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Autores principales: Ueno, Hiroki, Norose, Kazumi, Kamimura, Teppei, Mihara, Keichiro, Yamasaki, Fumiyuki, Hikosaka, Kenji, J. Amatya, Vishwa, Takeshima, Yukio, Kurisu, Kaoru, Maruyama, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522404/
https://www.ncbi.nlm.nih.gov/pubmed/30568116
http://dx.doi.org/10.2169/internalmedicine.1156-18
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author Ueno, Hiroki
Norose, Kazumi
Kamimura, Teppei
Mihara, Keichiro
Yamasaki, Fumiyuki
Hikosaka, Kenji
J. Amatya, Vishwa
Takeshima, Yukio
Kurisu, Kaoru
Maruyama, Hirofumi
author_facet Ueno, Hiroki
Norose, Kazumi
Kamimura, Teppei
Mihara, Keichiro
Yamasaki, Fumiyuki
Hikosaka, Kenji
J. Amatya, Vishwa
Takeshima, Yukio
Kurisu, Kaoru
Maruyama, Hirofumi
author_sort Ueno, Hiroki
collection PubMed
description We herein report the case of a 60-year-old man with a “target sign” in the left frontal lobe on magnetic resonance imaging (MRI), which is thought to be a specific sign of cerebral toxoplasmosis. (18)F-fluorodeoxyglucose-positron emission tomography showed no increased uptake, and (201)Tl-single photon emission computed tomography showed the focal uptake in the left frontal lesion. On a brain biopsy, the patient was given a definitive diagnosis of brain metastasis from diffuse large B-cell lymphoma, and cerebral toxoplasmosis was excluded. In the present case, multilayer intensities on MRI may reflect the fast-growing nature of this tumor.
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spelling pubmed-65224042019-05-20 Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the “Target Sign” Ueno, Hiroki Norose, Kazumi Kamimura, Teppei Mihara, Keichiro Yamasaki, Fumiyuki Hikosaka, Kenji J. Amatya, Vishwa Takeshima, Yukio Kurisu, Kaoru Maruyama, Hirofumi Intern Med Case Report We herein report the case of a 60-year-old man with a “target sign” in the left frontal lobe on magnetic resonance imaging (MRI), which is thought to be a specific sign of cerebral toxoplasmosis. (18)F-fluorodeoxyglucose-positron emission tomography showed no increased uptake, and (201)Tl-single photon emission computed tomography showed the focal uptake in the left frontal lesion. On a brain biopsy, the patient was given a definitive diagnosis of brain metastasis from diffuse large B-cell lymphoma, and cerebral toxoplasmosis was excluded. In the present case, multilayer intensities on MRI may reflect the fast-growing nature of this tumor. The Japanese Society of Internal Medicine 2018-12-18 2019-04-15 /pmc/articles/PMC6522404/ /pubmed/30568116 http://dx.doi.org/10.2169/internalmedicine.1156-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ueno, Hiroki
Norose, Kazumi
Kamimura, Teppei
Mihara, Keichiro
Yamasaki, Fumiyuki
Hikosaka, Kenji
J. Amatya, Vishwa
Takeshima, Yukio
Kurisu, Kaoru
Maruyama, Hirofumi
Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the “Target Sign”
title Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the “Target Sign”
title_full Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the “Target Sign”
title_fullStr Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the “Target Sign”
title_full_unstemmed Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the “Target Sign”
title_short Metastatic Malignant Lymphoma Mimicking Cerebral Toxoplasmosis with the “Target Sign”
title_sort metastatic malignant lymphoma mimicking cerebral toxoplasmosis with the “target sign”
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522404/
https://www.ncbi.nlm.nih.gov/pubmed/30568116
http://dx.doi.org/10.2169/internalmedicine.1156-18
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