Chronic Pulmonary Aspergillosis with Pleuroparenchymal Fibroelastosis-like Features

A 64-year-old man who presented with repeated bouts of pneumothorax was admitted to our hospital because of gradually progressive dyspnea and repeated episodes of a fever. The physiological, radiological and pathological findings were consistent with pleuroparenchymal fibroelastosis (PPFE). In addit...

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Autores principales: Kushima, Hisako, Ishii, Hiroshi, Kinoshita, Yoshiaki, Fujita, Masaki, Watanabe, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522409/
https://www.ncbi.nlm.nih.gov/pubmed/30568135
http://dx.doi.org/10.2169/internalmedicine.1930-18
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author Kushima, Hisako
Ishii, Hiroshi
Kinoshita, Yoshiaki
Fujita, Masaki
Watanabe, Kentaro
author_facet Kushima, Hisako
Ishii, Hiroshi
Kinoshita, Yoshiaki
Fujita, Masaki
Watanabe, Kentaro
author_sort Kushima, Hisako
collection PubMed
description A 64-year-old man who presented with repeated bouts of pneumothorax was admitted to our hospital because of gradually progressive dyspnea and repeated episodes of a fever. The physiological, radiological and pathological findings were consistent with pleuroparenchymal fibroelastosis (PPFE). In addition, the serum-specific precipitating antibody for Aspergillus was positive. After the administration of voriconazole, a marked improvement was observed in the imaging and physiological findings. Given this clinical course, we diagnosed the patient with PPFE secondary to aspergillosis. The present case suggests that a therapeutic approach based on the cause of secondary PPFE may improve the prognosis of PPFE.
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spelling pubmed-65224092019-05-20 Chronic Pulmonary Aspergillosis with Pleuroparenchymal Fibroelastosis-like Features Kushima, Hisako Ishii, Hiroshi Kinoshita, Yoshiaki Fujita, Masaki Watanabe, Kentaro Intern Med Case Report A 64-year-old man who presented with repeated bouts of pneumothorax was admitted to our hospital because of gradually progressive dyspnea and repeated episodes of a fever. The physiological, radiological and pathological findings were consistent with pleuroparenchymal fibroelastosis (PPFE). In addition, the serum-specific precipitating antibody for Aspergillus was positive. After the administration of voriconazole, a marked improvement was observed in the imaging and physiological findings. Given this clinical course, we diagnosed the patient with PPFE secondary to aspergillosis. The present case suggests that a therapeutic approach based on the cause of secondary PPFE may improve the prognosis of PPFE. The Japanese Society of Internal Medicine 2018-12-18 2019-04-15 /pmc/articles/PMC6522409/ /pubmed/30568135 http://dx.doi.org/10.2169/internalmedicine.1930-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kushima, Hisako
Ishii, Hiroshi
Kinoshita, Yoshiaki
Fujita, Masaki
Watanabe, Kentaro
Chronic Pulmonary Aspergillosis with Pleuroparenchymal Fibroelastosis-like Features
title Chronic Pulmonary Aspergillosis with Pleuroparenchymal Fibroelastosis-like Features
title_full Chronic Pulmonary Aspergillosis with Pleuroparenchymal Fibroelastosis-like Features
title_fullStr Chronic Pulmonary Aspergillosis with Pleuroparenchymal Fibroelastosis-like Features
title_full_unstemmed Chronic Pulmonary Aspergillosis with Pleuroparenchymal Fibroelastosis-like Features
title_short Chronic Pulmonary Aspergillosis with Pleuroparenchymal Fibroelastosis-like Features
title_sort chronic pulmonary aspergillosis with pleuroparenchymal fibroelastosis-like features
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522409/
https://www.ncbi.nlm.nih.gov/pubmed/30568135
http://dx.doi.org/10.2169/internalmedicine.1930-18
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