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Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) have the ability of differentiating into functional cardiomyocytes (CMs) for cell replacement therapy, tissue engineering, drug discovery and toxicity screening. From a scale-free, co-expression network analysis of transcr...
Autores principales: | Chow, Maggie Zi-Ying, Sadrian, Stephanie N., Keung, Wendy, Geng, Lin, Ren, Lihuan, Kong, Chi-Wing, Wong, Andy On-Tik, Hulot, Jean-Sebastien, Chen, Christopher S., Costa, Kevin D., Hajjar, Roger J., Li, Ronald A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522495/ https://www.ncbi.nlm.nih.gov/pubmed/31097748 http://dx.doi.org/10.1038/s41598-019-42953-w |
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