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A lasered mouse model of retinal degeneration displays progressive outer retinal pathology providing insights into early geographic atrophy
Early stages of geographic atrophy (GA) age-related macular degeneration is characterised by the demise of photoreceptors, which precedes the loss of underlying retinal pigment epithelial (RPE) cells. Sight-loss due to GA has no effective treatment; reflecting both the complexity of the disease and...
Autores principales: | Ibbett, Paul, Goverdhan, Srinivas V., Pipi, Elena, Chouhan, Joe K., Keeling, Eloise, Angus, Elizabeth M., Scott, Jenny A., Gatherer, Maureen, Page, Anton, Teeling, Jessica L., Lotery, Andrew J., Arjuna Ratnayaka, J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522499/ https://www.ncbi.nlm.nih.gov/pubmed/31097765 http://dx.doi.org/10.1038/s41598-019-43906-z |
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