TRPV4-induced inflammatory response is involved in neuronal death in pilocarpine model of temporal lobe epilepsy in mice

Activation of transient receptor potential vanilloid 4 (TRPV4) induces neuronal injury. TRPV4 activation enhances inflammatory response and promotes the proinflammatory cytokine release in various types of tissue and cells. Hyperneuroinflammation contributes to neuronal damage in epilepsy. Herein, w...

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Detalles Bibliográficos
Autores principales: Wang, Zhouqing, Zhou, Li, An, Dong, Xu, Weixing, Wu, Chunfeng, Sha, Sha, Li, Yingchun, Zhu, Yichao, Chen, Aidong, Du, Yimei, Chen, Lei, Chen, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522539/
https://www.ncbi.nlm.nih.gov/pubmed/31097691
http://dx.doi.org/10.1038/s41419-019-1612-3

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