Cargando…

M2 macrophages promote NSCLC metastasis by upregulating CRYAB

The mechanism by which tumor-associated macrophages (TAMs) affect cancer progression is not fully understood. This study developed a microfluidic-based co-culture device to mimic the tumor microenvironment to assess TAM effects on invasion and metastasis in NSCLC. The results showed lung carcinoma c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Zhe, Song, Jing, Hao, Junxia, Zhao, Hui, Du, Xiaohui, Li, Encheng, Kuang, Yanbin, Yang, Fuquan, Wang, Wei, Deng, Jiong, Wang, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522541/ https://www.ncbi.nlm.nih.gov/pubmed/31097690 http://dx.doi.org/10.1038/s41419-019-1618-x

Ejemplares similares

MiRNA-671-5p Promotes prostate cancer development and metastasis by targeting NFIA/CRYAB axis
por: Zhu, Zhiguo, et al.
Publicado: (2020)

Progression of the role of CRYAB in signaling pathways and cancers
por: Zhang, JunFei, et al.
Publicado: (2019)

CD47 Promotes Tumor Invasion and Metastasis in Non-small Cell Lung Cancer
por: Zhao, Hui, et al.
Publicado: (2016)

Missense Mutations in CRYAB Are Liable for Recessive Congenital Cataracts
por: Jiaox, Xiaodong, et al.
Publicado: (2015)

CRYAB predicts clinical prognosis and is associated with immunocyte infiltration in colorectal cancer
por: Deng, Junsheng, et al.
Publicado: (2021)

cDNA, genomic sequence and overexpression of crystallin alpha-B Gene (CRYAB) of the Giant Panda
por: Hou, Yi-ling, et al.
Publicado: (2008)

Correction: Missense Mutations in CRYAB Are Liable for Recessive Congenital Cataracts
por: Jiao, Xiaodong, et al.
Publicado: (2017)

Presence and activation of pro-inflammatory macrophages are associated with CRYAB expression in vitro and after peripheral nerve injury
por: Lim, Erin-Mai F., et al.
Publicado: (2021)

Novel Secreted Protein of Mycoplasma bovis MbovP280 Induces Macrophage Apoptosis Through CRYAB
por: Zhao, Gang, et al.
Publicado: (2021)

Krüppel-like factor 4 promotes human osteosarcoma growth and metastasis via regulating CRYAB expression
por: Zhang, Lu, et al.
Publicado: (2016)

Expression of CRYAB with the angiogenesis and poor prognosis for human gastric cancer
por: Tao, Xiaoying, et al.
Publicado: (2019)

The role of CRYAB in tumor prognosis and immune infiltration: A Pan-cancer analysis
por: Cheng, Lang, et al.
Publicado: (2023)

Senolysis induced by 25-hydroxycholesterol targets CRYAB in multiple cell types
por: Limbad, Chandani, et al.
Publicado: (2022)

Deletion of Cryab increases the vulnerability of mice to the addiction-like effects of the cannabinoid JWH-018 via upregulation of striatal NF-κB expression
por: Sayson, Leandro Val, et al.
Publicado: (2023)

Human Mutated MYOT and CRYAB Genes Cause a Myopathic Phenotype in Zebrafish
por: Cannone, Elena, et al.
Publicado: (2023)

Role of methylation-related genes CRYAB and SLC39A11 in the occurrence and development of lung adenocarcinoma
por: Wang, Shuying, et al.
Publicado: (2022)

Rosemary Reduces Heat Stress by Inducing CRYAB and HSP70 Expression in Broiler Chickens
por: Tang, Shu, et al.
Publicado: (2018)

A novel dominant mutation in CRYAB gene leading to a severe phenotype with childhood onset
por: Marcos, Ana T., et al.
Publicado: (2020)

Association of single nucleotide polymorphism variations in CRYAA and CRYAB genes with congenital cataract in Pakistani population
por: Jarwar, Priya, et al.
Publicado: (2022)

Case report: Fatal infantile hypertonic myofibrillar myopathy with compound heterozygous mutations in the CRYAB gene
por: Zhang, Shan-shan, et al.
Publicado: (2023)

PIK3R1, SPNB2, and CRYAB as Potential Biomarkers for Patients with Diabetes and Developing Acute Myocardial Infarction
por: Zheng, Yue, et al.
Publicado: (2021)

Novel mycoplasma nucleomodulin MbovP475 decreased cell viability by regulating expression of CRYAB and MCF2L2
por: Zhao, Gang, et al.
Publicado: (2022)

Identification of a novel CRYAB mutation associated with autosomal recessive juvenile cataract in a Saudi family
por: Safieh, L Abu, et al.
Publicado: (2009)

A novel mutation in CRYAB associated with autosomal dominant congenital nuclear cataract in a Chinese family
por: Chen, Qiang, et al.
Publicado: (2009)

Long noncoding RNA AFAP1-AS1 is upregulated in NSCLC and associated with lymph node metastasis and poor prognosis
por: Leng, Xuechun, et al.
Publicado: (2018)

Restoration of miR-23a expression by chidamide sensitizes CML cells to imatinib treatment with concomitant downregulation of CRYAB
por: Zhu, Xunxun, et al.
Publicado: (2022)

Mechanism of Action of VP1-001 in cryAB(R120G)-Associated and Age-Related Cataracts
por: Molnar, Kathleen S., et al.
Publicado: (2019)

M2 macrophages, but not M1 macrophages, support megakaryopoiesis by upregulating PI3K-AKT pathway activity
por: Zhao, Hong-Yan, et al.
Publicado: (2021)

Evolutionary Characteristics and Immunologic Divergence of Lung and Brain Metastasis Lesions in NSCLC
por: Xie, Tongji, et al.
Publicado: (2023)

Clinical Significance of Has_circ_0060937 in Bone Metastasis of NSCLC
por: Zhang, Jiangnan, et al.
Publicado: (2020)

Correlations of single nucleotide polymorphisms of CRYAA and CRYAB genes with the risk and clinicopathological features of children suffering from congenital cataract
por: Cui, Xian-Jin, et al.
Publicado: (2017)

Inhibition of miR-450b-5p ameliorates hepatic ischemia/reperfusion injury via targeting CRYAB
por: Huang, Zuotian, et al.
Publicado: (2020)

IDO1 Promotes the Progression of NSCLC by Regulating the Polarization of M2 Macrophages
por: Chen, Xiao, et al.
Publicado: (2023)

PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC
por: Du, Hongzhi, et al.
Publicado: (2017)

Lower Blood Calcium Associates with Unfavorable Prognosis and Predicts for Bone Metastasis in NSCLC
por: Shen, Hongchang, et al.
Publicado: (2012)

Systematic analysis of mRNA expression profiles in NSCLC cell lines to screen metastasis-related genes
por: Liu, Ying, et al.
Publicado: (2016)

Adipocyte abundances of CES1, CRYAB, ENO1 and GANAB are modified in-vitro by glucose restriction and are associated with cellular remodelling during weight regain
por: Qiao, Qi, et al.
Publicado: (2019)

Glutathione peroxidase 4‐dependent glutathione high‐consumption drives acquired platinum chemoresistance in lung cancer‐derived brain metastasis
por: Liu, Wenwen, et al.
Publicado: (2021)

Long Noncoding RNA lnc-TSSK2-8 Activates Canonical Wnt/β-Catenin Signaling Through Small Heat Shock Proteins HSPA6 and CRYAB
por: Fa, Jingjing, et al.
Publicado: (2021)

CRYAB promotes osteogenic differentiation of human bone marrow stem cells via stabilizing β‐catenin and promoting the Wnt signalling
por: Zhu, Bin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9jjon45riu7r2fl4p0s98huu6p