Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers

Although promoter-associated CpG islands have been established as targets of DNA methylation changes in cancer, previous studies suggest that epigenetic dysregulation outside the promoter region may be more closely associated with transcriptional changes. Here we examine DNA methylation, chromatin m...

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Detalles Bibliográficos
Autores principales: Ando, Mizuo, Saito, Yuki, Xu, Guorong, Bui, Nam Q., Medetgul-Ernar, Kate, Pu, Minya, Fisch, Kathleen, Ren, Shuling, Sakai, Akihiro, Fukusumi, Takahito, Liu, Chao, Haft, Sunny, Pang, John, Mark, Adam, Gaykalova, Daria A., Guo, Theresa, Favorov, Alexander V., Yegnasubramanian, Srinivasan, Fertig, Elana J., Ha, Patrick, Tamayo, Pablo, Yamasoba, Tatsuya, Ideker, Trey, Messer, Karen, Califano, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522544/
https://www.ncbi.nlm.nih.gov/pubmed/31097695
http://dx.doi.org/10.1038/s41467-019-09937-w

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