Secondary dengue retinitis with associated occlusive retinal vasculitis

BACKGROUND: Dengue is endemic in tropical countries. Secondary dengue infections are generally more dangerous as they lead to an exaggerated response in the patient due to the severe immunological response caused by antibody-dependent enhancement (ADE) leading to severe ocular manifestations like re...

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Autores principales: Koundanya, Vikram Vinayak, Chowdhary, Neha, Agarwal, Manisha, Katre, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522610/
https://www.ncbi.nlm.nih.gov/pubmed/31098778
http://dx.doi.org/10.1186/s12348-019-0175-x
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author Koundanya, Vikram Vinayak
Chowdhary, Neha
Agarwal, Manisha
Katre, Prashant
author_facet Koundanya, Vikram Vinayak
Chowdhary, Neha
Agarwal, Manisha
Katre, Prashant
author_sort Koundanya, Vikram Vinayak
collection PubMed
description BACKGROUND: Dengue is endemic in tropical countries. Secondary dengue infections are generally more dangerous as they lead to an exaggerated response in the patient due to the severe immunological response caused by antibody-dependent enhancement (ADE) leading to severe ocular manifestations like retinitis. RESULTS: A 42-year-old female was diagnosed as secondary dengue retinitis with associated retinal vasculitis based on her past history, clinical presentation, IgG/IgM ratio, and enzyme-linked immunosorbent assay (ELISA) test for dengue and was successfully treated with oral corticosteroids. CONCLUSION: Secondary dengue infection may manifest as retinitis with signs of microvascular occlusions in the retina. A high level of suspicion and IgG/IgM ratio may help in confirming the diagnosis.
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spelling pubmed-65226102019-06-05 Secondary dengue retinitis with associated occlusive retinal vasculitis Koundanya, Vikram Vinayak Chowdhary, Neha Agarwal, Manisha Katre, Prashant J Ophthalmic Inflamm Infect Brief Report BACKGROUND: Dengue is endemic in tropical countries. Secondary dengue infections are generally more dangerous as they lead to an exaggerated response in the patient due to the severe immunological response caused by antibody-dependent enhancement (ADE) leading to severe ocular manifestations like retinitis. RESULTS: A 42-year-old female was diagnosed as secondary dengue retinitis with associated retinal vasculitis based on her past history, clinical presentation, IgG/IgM ratio, and enzyme-linked immunosorbent assay (ELISA) test for dengue and was successfully treated with oral corticosteroids. CONCLUSION: Secondary dengue infection may manifest as retinitis with signs of microvascular occlusions in the retina. A high level of suspicion and IgG/IgM ratio may help in confirming the diagnosis. Springer Berlin Heidelberg 2019-05-16 /pmc/articles/PMC6522610/ /pubmed/31098778 http://dx.doi.org/10.1186/s12348-019-0175-x Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Brief Report
Koundanya, Vikram Vinayak
Chowdhary, Neha
Agarwal, Manisha
Katre, Prashant
Secondary dengue retinitis with associated occlusive retinal vasculitis
title Secondary dengue retinitis with associated occlusive retinal vasculitis
title_full Secondary dengue retinitis with associated occlusive retinal vasculitis
title_fullStr Secondary dengue retinitis with associated occlusive retinal vasculitis
title_full_unstemmed Secondary dengue retinitis with associated occlusive retinal vasculitis
title_short Secondary dengue retinitis with associated occlusive retinal vasculitis
title_sort secondary dengue retinitis with associated occlusive retinal vasculitis
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522610/
https://www.ncbi.nlm.nih.gov/pubmed/31098778
http://dx.doi.org/10.1186/s12348-019-0175-x
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AT katreprashant secondarydengueretinitiswithassociatedocclusiveretinalvasculitis

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