Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa

Serious infections such as endocarditis due to extremely drug-resistance gram-negative bacteria are an increasing challenge. Here, we present successful adjunctive use of cefiderocol for a patient with persistently bacteremic healthcare-associated native aortic valve endocarditis due to an extended-...

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Autores principales: Edgeworth, Jonathan D, Merante, Domenico, Patel, Sanjay, Young, Christopher, Jones, Paul, Vithlani, Seema, Wyncoll, Duncan, Roberts, Peter, Jones, Andrew, Den Nagata, Tsutae, Ariyasu, Mari, Livermore, David M, Beale, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522681/
https://www.ncbi.nlm.nih.gov/pubmed/30418554
http://dx.doi.org/10.1093/cid/ciy963
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author Edgeworth, Jonathan D
Merante, Domenico
Patel, Sanjay
Young, Christopher
Jones, Paul
Vithlani, Seema
Wyncoll, Duncan
Roberts, Peter
Jones, Andrew
Den Nagata, Tsutae
Ariyasu, Mari
Livermore, David M
Beale, Richard
author_facet Edgeworth, Jonathan D
Merante, Domenico
Patel, Sanjay
Young, Christopher
Jones, Paul
Vithlani, Seema
Wyncoll, Duncan
Roberts, Peter
Jones, Andrew
Den Nagata, Tsutae
Ariyasu, Mari
Livermore, David M
Beale, Richard
author_sort Edgeworth, Jonathan D
collection PubMed
description Serious infections such as endocarditis due to extremely drug-resistance gram-negative bacteria are an increasing challenge. Here, we present successful adjunctive use of cefiderocol for a patient with persistently bacteremic healthcare-associated native aortic valve endocarditis due to an extended-spectrum beta-lactamase–positive Pseudomonas aeruginosa susceptible in vitro only to colistin, following failure of conventional therapeutic options.
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spelling pubmed-65226812019-05-21 Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa Edgeworth, Jonathan D Merante, Domenico Patel, Sanjay Young, Christopher Jones, Paul Vithlani, Seema Wyncoll, Duncan Roberts, Peter Jones, Andrew Den Nagata, Tsutae Ariyasu, Mari Livermore, David M Beale, Richard Clin Infect Dis Brief Reports Serious infections such as endocarditis due to extremely drug-resistance gram-negative bacteria are an increasing challenge. Here, we present successful adjunctive use of cefiderocol for a patient with persistently bacteremic healthcare-associated native aortic valve endocarditis due to an extended-spectrum beta-lactamase–positive Pseudomonas aeruginosa susceptible in vitro only to colistin, following failure of conventional therapeutic options. Oxford University Press 2019-06-01 2018-11-12 /pmc/articles/PMC6522681/ /pubmed/30418554 http://dx.doi.org/10.1093/cid/ciy963 Text en © The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Reports
Edgeworth, Jonathan D
Merante, Domenico
Patel, Sanjay
Young, Christopher
Jones, Paul
Vithlani, Seema
Wyncoll, Duncan
Roberts, Peter
Jones, Andrew
Den Nagata, Tsutae
Ariyasu, Mari
Livermore, David M
Beale, Richard
Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa
title Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa
title_full Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa
title_fullStr Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa
title_full_unstemmed Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa
title_short Compassionate Use of Cefiderocol as Adjunctive Treatment of Native Aortic Valve Endocarditis Due to Extremely Drug-resistant Pseudomonas aeruginosa
title_sort compassionate use of cefiderocol as adjunctive treatment of native aortic valve endocarditis due to extremely drug-resistant pseudomonas aeruginosa
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522681/
https://www.ncbi.nlm.nih.gov/pubmed/30418554
http://dx.doi.org/10.1093/cid/ciy963
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