Increased FoxO3a expression prevents osteoblast differentiation and matrix calcification

Forkhead Box O transcription factors play important roles in bone metabolism by defending against oxidative stress and apoptosis. FoxO3a is of special interest as it is the predominant isoform expressed in bone. In osteoblasts, the administration of 1,25 dihydroxyvitamin D(3) (1,25D(3)) increases Fo...

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Detalles Bibliográficos
Autores principales: Tang, Kathy C., Pan, Wanling, Doschak, Michael R., Alexander, R. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522754/
https://www.ncbi.nlm.nih.gov/pubmed/31193232
http://dx.doi.org/10.1016/j.bonr.2019.100206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522754/
https://www.ncbi.nlm.nih.gov/pubmed/31193232
http://dx.doi.org/10.1016/j.bonr.2019.100206

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