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Increased FoxO3a expression prevents osteoblast differentiation and matrix calcification
Forkhead Box O transcription factors play important roles in bone metabolism by defending against oxidative stress and apoptosis. FoxO3a is of special interest as it is the predominant isoform expressed in bone. In osteoblasts, the administration of 1,25 dihydroxyvitamin D(3) (1,25D(3)) increases Fo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522754/ https://www.ncbi.nlm.nih.gov/pubmed/31193232 http://dx.doi.org/10.1016/j.bonr.2019.100206 |