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Hepatic Lysosomal iNOS Activity Impairs Autophagy in Obesity

BACKGROUND & AIMS: The lysosome is an acidic organelle that is important for maintaining cellular and metabolic homeostasis in hepatocytes. Lysosomal dysfunction and chronic inflammation coexist, and both contribute to obesity-associated hepatic insulin resistance. However, in the context of obe...

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Detalles Bibliográficos
Autores principales:	Qian, Qingwen, Zhang, Zeyuan, Li, Mark, Savage, Kalie, Cheng, Dechun, Rauckhorst, Adam J., Ankrum, James A., Taylor, Eric B., Ding, Wen-xing, Xiao, Yi, Cao, Huo-jun, Yang, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522853/ https://www.ncbi.nlm.nih.gov/pubmed/30926581 http://dx.doi.org/10.1016/j.jcmgh.2019.03.005

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