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Inactivation of Streptococcus mutans genes lytST and dltAD impairs its pathogenicity in vivo
Background: Streptococcus mutans orchestrates the development of a biofilm that causes dental caries in the presence of dietary sucrose, and, in the bloodstream, S. mutans can cause systemic infections. The development of a cariogenic biofilm is dependent on the formation of an extracellular matrix...
Autores principales: | Castillo Pedraza, Midian C., Rosalen, Pedro L., de Castilho, Aline Rogéria Freire, Freires, Irlan de Almeida, de Sales Leite, Luana, Faustoferri, Roberta C., Quivey Jr, Robert G., Klein, Marlise I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522913/ https://www.ncbi.nlm.nih.gov/pubmed/31143407 http://dx.doi.org/10.1080/20002297.2019.1607505 |
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