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Characterization and validation of an intra‐fraction motion management system for masked‐based radiosurgery

PURPOSE: Characterize the intra‐fraction motion management (IFMM) system found on the Gamma Knife Icon (GKI), including spatial accuracy, latency, temporal performance, and overall effect on delivered dose. METHODS: A phantom was constructed, consisting of a three‐axis translation mount, a remote mo...

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Autores principales: Knutson, Nels C., Hawkins, Brad J., Bollinger, Douglas, Goddu, S. Murty, Kavanaugh, James A., Santanam, Lakshmi, Mitchell, Timothy J., Zoberi, Jacqueline E., Tsien, Christina, Huang, Jiayi, Robinson, Clifford G., Perkins, Stephanie M., Dowling, Joshua L., Chicoine, Michael R., Rich, Keith M., Dunn, Gavin P., Mutic, Sasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522989/
https://www.ncbi.nlm.nih.gov/pubmed/31055877
http://dx.doi.org/10.1002/acm2.12573
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author Knutson, Nels C.
Hawkins, Brad J.
Bollinger, Douglas
Goddu, S. Murty
Kavanaugh, James A.
Santanam, Lakshmi
Mitchell, Timothy J.
Zoberi, Jacqueline E.
Tsien, Christina
Huang, Jiayi
Robinson, Clifford G.
Perkins, Stephanie M.
Dowling, Joshua L.
Chicoine, Michael R.
Rich, Keith M.
Dunn, Gavin P.
Mutic, Sasa
author_facet Knutson, Nels C.
Hawkins, Brad J.
Bollinger, Douglas
Goddu, S. Murty
Kavanaugh, James A.
Santanam, Lakshmi
Mitchell, Timothy J.
Zoberi, Jacqueline E.
Tsien, Christina
Huang, Jiayi
Robinson, Clifford G.
Perkins, Stephanie M.
Dowling, Joshua L.
Chicoine, Michael R.
Rich, Keith M.
Dunn, Gavin P.
Mutic, Sasa
author_sort Knutson, Nels C.
collection PubMed
description PURPOSE: Characterize the intra‐fraction motion management (IFMM) system found on the Gamma Knife Icon (GKI), including spatial accuracy, latency, temporal performance, and overall effect on delivered dose. METHODS: A phantom was constructed, consisting of a three‐axis translation mount, a remote motorized flipper, and a thermoplastic sphere surrounding a radiation detector. An infrared marker was placed on the translation mount secured to the flipper. The spatial accuracy of the IFMM was measured via the translation mount in all Cartesian planes. The detector was centered at the radiation focal point. A remote signal was used to move the marker out of the IFMM tolerance and pause the beam. A two‐channel electrometer was used to record the signals from the detector and the flipper when motion was signaled. These signals determined the latency and temporal performance of the GKI. RESULTS: The spatial accuracy of the IFMM was found to be <0.1 mm. The measured latency was <200 ms. The dose difference with five interruptions was <0.5%. CONCLUSION: This work provides a quantitative characterization of the GKI IFMM system as required by the Nuclear Regulatory Commission. This provides a methodology for GKI users to satisfy these requirements using common laboratory equipment in lieu of a commercial solution.
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spelling pubmed-65229892019-05-24 Characterization and validation of an intra‐fraction motion management system for masked‐based radiosurgery Knutson, Nels C. Hawkins, Brad J. Bollinger, Douglas Goddu, S. Murty Kavanaugh, James A. Santanam, Lakshmi Mitchell, Timothy J. Zoberi, Jacqueline E. Tsien, Christina Huang, Jiayi Robinson, Clifford G. Perkins, Stephanie M. Dowling, Joshua L. Chicoine, Michael R. Rich, Keith M. Dunn, Gavin P. Mutic, Sasa J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: Characterize the intra‐fraction motion management (IFMM) system found on the Gamma Knife Icon (GKI), including spatial accuracy, latency, temporal performance, and overall effect on delivered dose. METHODS: A phantom was constructed, consisting of a three‐axis translation mount, a remote motorized flipper, and a thermoplastic sphere surrounding a radiation detector. An infrared marker was placed on the translation mount secured to the flipper. The spatial accuracy of the IFMM was measured via the translation mount in all Cartesian planes. The detector was centered at the radiation focal point. A remote signal was used to move the marker out of the IFMM tolerance and pause the beam. A two‐channel electrometer was used to record the signals from the detector and the flipper when motion was signaled. These signals determined the latency and temporal performance of the GKI. RESULTS: The spatial accuracy of the IFMM was found to be <0.1 mm. The measured latency was <200 ms. The dose difference with five interruptions was <0.5%. CONCLUSION: This work provides a quantitative characterization of the GKI IFMM system as required by the Nuclear Regulatory Commission. This provides a methodology for GKI users to satisfy these requirements using common laboratory equipment in lieu of a commercial solution. John Wiley and Sons Inc. 2019-05-04 /pmc/articles/PMC6522989/ /pubmed/31055877 http://dx.doi.org/10.1002/acm2.12573 Text en © 2019 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Knutson, Nels C.
Hawkins, Brad J.
Bollinger, Douglas
Goddu, S. Murty
Kavanaugh, James A.
Santanam, Lakshmi
Mitchell, Timothy J.
Zoberi, Jacqueline E.
Tsien, Christina
Huang, Jiayi
Robinson, Clifford G.
Perkins, Stephanie M.
Dowling, Joshua L.
Chicoine, Michael R.
Rich, Keith M.
Dunn, Gavin P.
Mutic, Sasa
Characterization and validation of an intra‐fraction motion management system for masked‐based radiosurgery
title Characterization and validation of an intra‐fraction motion management system for masked‐based radiosurgery
title_full Characterization and validation of an intra‐fraction motion management system for masked‐based radiosurgery
title_fullStr Characterization and validation of an intra‐fraction motion management system for masked‐based radiosurgery
title_full_unstemmed Characterization and validation of an intra‐fraction motion management system for masked‐based radiosurgery
title_short Characterization and validation of an intra‐fraction motion management system for masked‐based radiosurgery
title_sort characterization and validation of an intra‐fraction motion management system for masked‐based radiosurgery
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522989/
https://www.ncbi.nlm.nih.gov/pubmed/31055877
http://dx.doi.org/10.1002/acm2.12573
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