Cargando…

Propolis Exerts an Anti-Inflammatory Effect on PMA-Differentiated THP-1 Cells via Inhibition of Purine Nucleoside Phosphorylase

Previous research has shown that propolis has immunomodulatory activity. Propolis extracts from different geographic origins were assessed for their anti-inflammatory activities by investigating their ability to alter the production of tumour necrosis factor-α (TNF-α) and the cytokines interleukin-1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alqarni, Abdulmalik M., Niwasabutra, Kanidta, Sahlan, Muhamad, Fearnley, Hugo, Fearnley, James, Ferro, Valerie A., Watson, David G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523283/ https://www.ncbi.nlm.nih.gov/pubmed/30995826 http://dx.doi.org/10.3390/metabo9040075

Ejemplares similares

Effect of Melittin on Metabolomic Profile and Cytokine Production in PMA-Differentiated THP-1 Cells
por: Alqarni, Abdulmalik M., et al.
Publicado: (2018)

Metabolomic Profiling of the Immune Stimulatory Effect of Eicosenoids on PMA-Differentiated THP-1 Cells
por: Alqarni, Abdulmalik M., et al.
Publicado: (2019)

8-Aminoinosine and 8-Aminohypoxanthine Inhibit Purine Nucleoside Phosphorylase and Exert Diuretic and Natriuretic Activity
por: Jackson, Edwin K., et al.
Publicado: (2022)

Purine nucleoside phosphorylase is associated with centrioles and basal bodies
Publicado: (1981)

Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases
por: Chaikuad, Apirat, et al.
Publicado: (2009)

Purine nucleoside phosphorylase deficiency in two unrelated Saudi patients
por: Alangari, Abdullah, et al.
Publicado: (2009)

Structural Determinants of the 5′-Methylthioinosine Specificity of Plasmodium Purine Nucleoside Phosphorylase
por: Donaldson, Teraya M., et al.
Publicado: (2014)

Purine nucleoside phosphorylase controls nicotinamide riboside metabolism in mammalian cells
por: Kropotov, Andrey, et al.
Publicado: (2022)

Efficient Synthesis of Purine Nucleoside Analogs by a New Trimeric Purine Nucleoside Phosphorylase from Aneurinibacillus migulanus AM007
por: Liu, Gaofei, et al.
Publicado: (2019)

Purine nucleoside phosphorylase inhibition ameliorates age-associated lower urinary tract dysfunctions
por: Birder, Lori A., et al.
Publicado: (2020)

Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate
por: D’Muniz Pereira, Humberto, et al.
Publicado: (2011)

Purine nucleoside phosphorylase inhibitors - an immunotherapy with novel mechanism of action for the treatment of melanoma
por: Bantia, Shanta
Publicado: (2015)

Partial Purine Nucleoside Phosphorylase Deficiency Helps Determine Minimal Activity Required for Immune and Neurological Development
por: Grunebaum, Eyal, et al.
Publicado: (2020)

Mitochondrial Basis for Immune Deficiency: Evidence from Purine Nucleoside Phosphorylase–Deficient Mice
por: Arpaia, Enrico, et al.
Publicado: (2000)

Metabolites of Purine Nucleoside Phosphorylase (NP) in Serum Have the Potential to Delineate Pancreatic Adenocarcinoma
por: Vareed, Shaiju K., et al.
Publicado: (2011)

Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors
por: Skácel, Jan, et al.
Publicado: (2023)

Synthesis of New 5′-Norcarbocyclic Aza/Deaza Purine Fleximers - Noncompetitive Inhibitors of E.coli Purine Nucleoside Phosphorylase
por: Khandazhinskaya, Anastasia, et al.
Publicado: (2022)

Functional and Structural Characterization of Purine Nucleoside Phosphorylase from Kluyveromyces lactis and Its Potential Applications in Reducing Purine Content in Food
por: Mahor, Durga, et al.
Publicado: (2016)

Adenosine deaminase and purine nucleoside phosphorylase activities in peripheral lymphocytes from patients with solid tumours.
por: Russo, M., et al.
Publicado: (1981)

Insights into Phosphate Cooperativity and Influence of Substrate Modifications on Binding and Catalysis of Hexameric Purine Nucleoside Phosphorylases
por: de Giuseppe, Priscila O., et al.
Publicado: (2012)

Purine Nucleoside Phosphorylase Targeted by Annexin V to Breast Cancer Vasculature for Enzyme Prodrug Therapy
por: Krais, John J., et al.
Publicado: (2013)

The ligand binding mechanism to purine nucleoside phosphorylase elucidated via molecular dynamics and machine learning
por: Decherchi, Sergio, et al.
Publicado: (2015)

Tricyclic Nucleobase Analogs and Their Ribosides as Substrates and Inhibitors of Purine-Nucleoside Phosphorylases III. Aminopurine Derivatives
por: Stachelska-Wierzchowska, Alicja, et al.
Publicado: (2020)

The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans
por: Tecle, Eillen, et al.
Publicado: (2021)

The structure of His-tagged Geobacillus stearothermophilus purine nucleoside phosphorylase reveals a ‘spanner in the works’
por: Given, Fiona M., et al.
Publicado: (2022)

Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity
por: Abt, Evan R., et al.
Publicado: (2022)

Cloning, purification and characterisation of a recombinant purine nucleoside phosphorylase from Bacillus halodurans Alk36
por: Visser, Daniel F., et al.
Publicado: (2010)

Tri-Cyclic Nucleobase Analogs and Their Ribosides as Substrates of Purine-Nucleoside Phosphorylases. II Guanine and Isoguanine Derivatives
por: Stachelska-Wierzchowska, Alicja, et al.
Publicado: (2019)

Early Diagnosis and Treatment of Purine Nucleoside Phosphorylase (PNP) Deficiency through TREC-Based Newborn Screening
por: Martín-Nalda, Andrea, et al.
Publicado: (2021)

Correction: The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans
por: Tecle, Eillen, et al.
Publicado: (2022)

Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium
por: Narczyk, Marta, et al.
Publicado: (2022)

Incorporation of extracellular 8-oxodG into DNA and RNA requires purine nucleoside phosphorylase in MCF-7 cells
por: Mundt, Janna M., et al.
Publicado: (2008)

Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: A tangible union against chemoresistant cancer
por: Singh, Preetinder P, et al.
Publicado: (2011)

In Vitro Immunomodulatory Activity of a Transition-State Analog Inhibitor of Human Purine Nucleoside Phosphorylase in Cutaneous Leishmaniasis
por: Carvalho, Natália Barbosa, et al.
Publicado: (2017)

Immunodeficiency, Motor Delay, and Hypouricemia Caused by a Novel Mutation of Purine Nucleoside Phosphorylase Gene in an Indian Infant
por: Shah, Nikit, et al.
Publicado: (2019)

Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis
por: Štefanić, Zoran, et al.
Publicado: (2018)

Antitumor effects of a dual-specific lentiviral vector carrying the Escherichia coli purine nucleoside phosphorylase gene
por: Wang, Xiaolong, et al.
Publicado: (2017)

A comprehensive method for determining cellular uptake of purine nucleoside phosphorylase and adenylosuccinate synthetase inhibitors by H. pylori
por: Wojtyś, Marta Ilona, et al.
Publicado: (2021)

Evaluating antitumor activity of Escherichia coli purine nucleoside phosphorylase against head and neck patient‐derived xenografts
por: Rab, Regina, et al.
Publicado: (2022)

Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases
por: Il’icheva, Irina A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t5nvk4slop7dhqvtm9sc0ftf4g