Cargando…

The Modulation of Chitosan-DNA Interaction by Concentration and pH in Solution

Chitosan has been widely used to prepare a DNA carrier for highly efficient and non-toxic gene therapy. In the present study, we investigated DNA charge neutralization and compaction by chitosan in solutions of various pH levels by dynamic light scattering (DLS), magnetic tweezers (MT), and atomic f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Fangqin, Wang, Yanwei, Yang, Guangcan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523332/ https://www.ncbi.nlm.nih.gov/pubmed/30970619 http://dx.doi.org/10.3390/polym11040646

Ejemplares similares

DNA Compaction and Charge Neutralization Regulated by Divalent Ions in very Low pH Solution
por: Gao, Tianyong, et al.
Publicado: (2019)

Demonstration of pH-controlled DNA–surfactant manipulation for biomolecules
por: Li, Na, et al.
Publicado: (2021)

pH Dependence of Chitosan Enzymolysis
por: Gohi, Bi Foua Claude Alain, et al.
Publicado: (2017)

Multivariable analysis of egg white protein-chitosan interaction: Influence of pH, temperature, biopolymers ratio, and ionic concentration
por: Wang, Yuemeng, et al.
Publicado: (2023)

Single Molecular Demonstration of Modulating Charge Inversion of DNA
por: Wang, Yanwei, et al.
Publicado: (2016)

Novel stable cytokine delivery system in physiological pH solution: chitosan oligosaccharide/heparin nanoparticles
por: Wang, Bin, et al.
Publicado: (2015)

Investigating the Influence of Magnesium Ions on p53–DNA Binding Using Atomic Force Microscopy
por: Chen, Yang, et al.
Publicado: (2017)

Pickering Emulsions Stabilized by Chitosan/Natural Acacia Gum Biopolymers: Effects of pH and Salt Concentrations
por: Adewunmi, Ahmad A., et al.
Publicado: (2022)

Liquid–Liquid Phase Separation Prediction of Proteins in Salt Solution by Deep Neural Network
por: Wei, Suwen, et al.
Publicado: (2022)

pH-Sensitive Chitosan Nanoparticles for Salivary Protein Delivery
por: Zhu, Yi, et al.
Publicado: (2021)

The importance of sialic acid, pH and ion concentration on the interaction of uromodulin and complement factor H
por: Bai, Lufeng, et al.
Publicado: (2021)

An Audit and Comparison of pH, Measured Concentration, and Particulate Matter in Mannitol and Hypertonic Saline Solutions
por: Carr, Christopher J., et al.
Publicado: (2021)

Fluoride and silver ion concentrations and pH in silver diamine fluoride solutions from Argentina
por: Rossi, Glenda, et al.
Publicado: (2022)

Vaginal pH measured in vivo: lactobacilli determine pH and lactic acid concentration
por: O’Hanlon, Deirdre Elizabeth, et al.
Publicado: (2019)

The promotion and suppression of DNA charge neutralization by the cosolute ectoine
por: Chen, Benteng, et al.
Publicado: (2019)

Visualization of DNA Damage and Protection by Atomic Force Microscopy in Liquid
por: Dai, Tinghui, et al.
Publicado: (2022)

DNA–Lysozyme Nanoarchitectonics: Quantitative Investigation on Charge Inversion and Compaction
por: Zhang, Rongyan, et al.
Publicado: (2022)

5′-(CGA)(n) sequence-assisted pH-controlled assembly of supramolecular DNA nanostructure
por: Yan, Yuting, et al.
Publicado: (2018)

Single molecular investigation of DNA looping and aggregation by restriction endonuclease BspMI
por: Wang, Yanwei, et al.
Publicado: (2014)

The incipient denaturation mechanism of DNA
por: Xu, Min, et al.
Publicado: (2022)

Pickering Emulsions Based on the pH-Responsive Assembly of Food-Grade Chitosan
por: Ahmed, Rizwan, et al.
Publicado: (2021)

Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity
por: Du, Jianyang, et al.
Publicado: (2009)

Bacterial interspecies interactions modulate pH-mediated antibiotic tolerance
por: Aranda-Díaz, Andrés, et al.
Publicado: (2020)

Study on the Interaction of Plasma-Polymerized Hydrogel Coatings with Aqueous Solutions of Different pH
por: Levien, Monique, et al.
Publicado: (2023)

Chitosan Gel Prepared with Citric Acid as the Food Acidulant: Effect of the Chitosan Concentration and Gel pH on Physicochemical and Functional Properties of Fish Protein Emulsion Sausages
por: Chattopadhyay, Kasturi, et al.
Publicado: (2023)

The Effects of pH and Excipients on Exenatide Stability in Solution
por: Benet, Alexander, et al.
Publicado: (2021)

Enhanced Gene Delivery Mediated by Low Molecular Weight Chitosan/DNA Complexes: Effect of pH and Serum
por: Nimesh, Surendra, et al.
Publicado: (2010)

DNA Compaction and Charge Inversion Induced by Organic Monovalent Ions
por: Xia, Wenyan, et al.
Publicado: (2017)

Carboxymethyl Chitosan and Its Hydrophobically Modified Derivative as pH-Switchable Emulsifiers
por: Kalliola, Simo, et al.
Publicado: (2018)

pH-Induced 3D Printable Chitosan Hydrogels for Soft Actuation
por: Maiz-Fernández, Sheila, et al.
Publicado: (2022)

Photochemical Generation of Methyl Chloride from Humic Aicd: Impacts of Precursor Concentration, Solution pH, Solution Salinity and Ferric Ion
por: Liu, Hui, et al.
Publicado: (2020)

pH-Sensitive Alginate/Carboxymethyl Chitosan/Aminated Chitosan Microcapsules for Efficient Encapsulation and Delivery of Diclofenac Sodium
por: Omer, Ahmed M., et al.
Publicado: (2021)

Effect of pH and concentration on the chemical stability and reaction kinetics of thiamine mononitrate and thiamine chloride hydrochloride in solution
por: Voelker, Adrienne L., et al.
Publicado: (2021)

The Mixing Counterion Effect on DNA Compaction and Charge Neutralization at Low Ionic Strength
por: Wang, Yanwei, et al.
Publicado: (2018)

pH Dependence of the Fluorescence Lifetime of FAD in Solution and in Cells
por: Islam, Md. Serajul, et al.
Publicado: (2013)

Unusual Salt and pH Induced Changes in Polyethylenimine Solutions
por: Curtis, Kimberly A., et al.
Publicado: (2016)

DNA Phase Transition in Charge Neutralization and Comformation Induced by Trivalent-Hydrolysed Metal Ions
por: Luo, Zhaoxu, et al.
Publicado: (2018)

Nanomechanical DNA Origami pH Sensors
por: Kuzuya, Akinori, et al.
Publicado: (2014)

pH-Controlled Assembly of DNA Tiles
por: Amodio, Alessia, et al.
Publicado: (2016)

Loss on drying, calcium concentration and pH of fluoride dentifrices
por: Brito, Arella Cristina Muniz, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_5h2qhpqh445gm6sqlrua2nii78