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Micro Milled Microfluidic Photoionization Detector for Volatile Organic Compounds
Government regulations and environmental conditions are pushing the development of improved miniaturized gas analyzers for volatile organic compounds. One of the many detectors used for gas analysis is the photoionization detector (PID). This paper presents the design and characterization of a micro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523568/ https://www.ncbi.nlm.nih.gov/pubmed/30934994 http://dx.doi.org/10.3390/mi10040228 |
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author | Rezende, Gustavo C. Le Calvé, Stéphane Brandner, Jürgen J. Newport, David |
author_facet | Rezende, Gustavo C. Le Calvé, Stéphane Brandner, Jürgen J. Newport, David |
author_sort | Rezende, Gustavo C. |
collection | PubMed |
description | Government regulations and environmental conditions are pushing the development of improved miniaturized gas analyzers for volatile organic compounds. One of the many detectors used for gas analysis is the photoionization detector (PID). This paper presents the design and characterization of a microfluidic photoionization detector (or µPID) fabricated using micro milling and electrical discharge machining techniques. This device has no glue and facilitates easy replacement of components. Two materials and fabrication techniques are proposed to produce a layer on the electrodes to protect from ultraviolet (UV) light and possible signal noise generation. Three different microchannels are tested experimentally and their results are compared. The channel with highest electrode area (31.17 mm²) and higher volume (6.47 µL) produces the highest raw signal and the corresponding estimated detection limit is 0.6 ppm for toluene without any amplification unit. |
format | Online Article Text |
id | pubmed-6523568 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-65235682019-06-03 Micro Milled Microfluidic Photoionization Detector for Volatile Organic Compounds Rezende, Gustavo C. Le Calvé, Stéphane Brandner, Jürgen J. Newport, David Micromachines (Basel) Article Government regulations and environmental conditions are pushing the development of improved miniaturized gas analyzers for volatile organic compounds. One of the many detectors used for gas analysis is the photoionization detector (PID). This paper presents the design and characterization of a microfluidic photoionization detector (or µPID) fabricated using micro milling and electrical discharge machining techniques. This device has no glue and facilitates easy replacement of components. Two materials and fabrication techniques are proposed to produce a layer on the electrodes to protect from ultraviolet (UV) light and possible signal noise generation. Three different microchannels are tested experimentally and their results are compared. The channel with highest electrode area (31.17 mm²) and higher volume (6.47 µL) produces the highest raw signal and the corresponding estimated detection limit is 0.6 ppm for toluene without any amplification unit. MDPI 2019-03-30 /pmc/articles/PMC6523568/ /pubmed/30934994 http://dx.doi.org/10.3390/mi10040228 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Rezende, Gustavo C. Le Calvé, Stéphane Brandner, Jürgen J. Newport, David Micro Milled Microfluidic Photoionization Detector for Volatile Organic Compounds |
title | Micro Milled Microfluidic Photoionization Detector for Volatile Organic Compounds |
title_full | Micro Milled Microfluidic Photoionization Detector for Volatile Organic Compounds |
title_fullStr | Micro Milled Microfluidic Photoionization Detector for Volatile Organic Compounds |
title_full_unstemmed | Micro Milled Microfluidic Photoionization Detector for Volatile Organic Compounds |
title_short | Micro Milled Microfluidic Photoionization Detector for Volatile Organic Compounds |
title_sort | micro milled microfluidic photoionization detector for volatile organic compounds |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523568/ https://www.ncbi.nlm.nih.gov/pubmed/30934994 http://dx.doi.org/10.3390/mi10040228 |
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