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Comparison of the Opn-CreER and Ck19-CreER Drivers in Bile Ducts of Normal and Injured Mouse Livers
Inducible cyclization recombinase (Cre) transgenic mouse strains are powerful tools for cell lineage tracing and tissue-specific knockout experiments. However, low efficiency or leaky expression can be important pitfalls. Here, we compared the efficiency and specificity of two commonly used cholangi...
Autores principales: | Lesaffer, Bram, Verboven, Elisabeth, Van Huffel, Leen, Moya, Iván M., van Grunsven, Leo A., Leclercq, Isabelle A., Lemaigre, Frédéric P., Halder, Georg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523626/ https://www.ncbi.nlm.nih.gov/pubmed/31027317 http://dx.doi.org/10.3390/cells8040380 |
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