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Next-Generation Sequencing Enables Spatiotemporal Resolution of Human Centromere Replication Timing

Centromeres serve a critical function in preserving genome integrity across sequential cell divisions, by mediating symmetric chromosome segregation. The repetitive, heterochromatic nature of centromeres is thought to be inhibitory to DNA replication, but has also led to their underrepresentation in...

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Detalles Bibliográficos
Autores principales:	Massey, Dashiell J., Kim, Dongsung, Brooks, Kayla E., Smolka, Marcus B., Koren, Amnon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523654/ https://www.ncbi.nlm.nih.gov/pubmed/30987063 http://dx.doi.org/10.3390/genes10040269

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