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Pharmacogenetics in the Treatment of Cardiovascular Diseases and Its Current Progress Regarding Implementation in the Clinical Routine

There is a special interest in the implementation of pharmacogenetics in clinical practice, although there are some barriers that are preventing this integration. A large part of these pharmacogenetic tests are focused on drugs used in oncology and psychiatry fields and for antiviral drugs. However,...

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Detalles Bibliográficos
Autores principales: Dávila-Fajardo, Cristina Lucía, Díaz-Villamarín, Xando, Antúnez-Rodríguez, Alba, Fernández-Gómez, Ana Estefanía, García-Navas, Paloma, Martínez-González, Luis Javier, Dávila-Fajardo, José Augusto, Cabeza Barrera, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523655/
https://www.ncbi.nlm.nih.gov/pubmed/30939847
http://dx.doi.org/10.3390/genes10040261
Descripción
Sumario:There is a special interest in the implementation of pharmacogenetics in clinical practice, although there are some barriers that are preventing this integration. A large part of these pharmacogenetic tests are focused on drugs used in oncology and psychiatry fields and for antiviral drugs. However, the scientific evidence is also high for other drugs used in other medical areas, for example, in cardiology. In this article, we discuss the evidence and guidelines currently available on pharmacogenetics for clopidogrel, warfarin, acenocoumarol, and simvastatin and its implementation in daily clinical practice.