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Characteristics of Skin Deposition of Itraconazole Solubilized in Cream Formulation
Itraconazole (ITZ) is an anti-fungal agent generally used to treat cutaneous mycoses. For efficient delivery of ITZ to the skin tissues, an oil-in-water (O/W) cream formulation was developed. The O/W cream base was designed based on the solubility measurement of ITZ in various excipients. A physical...
Autores principales: | Kim, Hyeongmin, Jung, Sukkyun, Yeo, Sooho, Kim, Dohyun, Na, Young Chae, Yun, Gyiae, Lee, Jaehwi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523664/ https://www.ncbi.nlm.nih.gov/pubmed/31013633 http://dx.doi.org/10.3390/pharmaceutics11040195 |
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