Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines

Greensporone A is a fungal secondary metabolite that has exhibited potential in vitro for anti-proliferative activity in vitro. We studied the anticancer activity of greensporone A in a panel of leukemic cell lines. Greensporone A-mediated inhibition of proliferation is found to be associated with t...

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Detalles Bibliográficos
Autores principales: Prabhu, Kirti S., Siveen, Kodappully S., Kuttikrishnan, Shilpa, Jochebeth, Anh, Ali, Tayyiba A., Elareer, Noor R., Iskandarani, Ahmad, Quaiyoom Khan, Abdul, Merhi, Maysaloun, Dermime, Said, El-Elimat, Tamam, Oberlies, Nicholas H., Alali, Feras Q., Steinhoff, Martin, Uddin, Shahab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523683/
https://www.ncbi.nlm.nih.gov/pubmed/30934922
http://dx.doi.org/10.3390/biom9040126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523683/
https://www.ncbi.nlm.nih.gov/pubmed/30934922
http://dx.doi.org/10.3390/biom9040126

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