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Regulation Is in the Air: The Relationship between Hypoxia and Epigenetics in Cancer

Hypoxia is an inherent condition of tumors and contributes to cancer development and progression. Hypoxia-inducible factors (HIFs) are the major transcription factors involved in response to low O(2) levels, orchestrating the expression of hundreds of genes involved in cancer hallmarks’ acquisition...

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Detalles Bibliográficos
Autores principales: Camuzi, Diego, de Amorim, Ísis Salviano Soares, Ribeiro Pinto, Luis Felipe, Oliveira Trivilin, Leonardo, Mencalha, André Luiz, Soares Lima, Sheila Coelho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523720/
https://www.ncbi.nlm.nih.gov/pubmed/30939818
http://dx.doi.org/10.3390/cells8040300