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Comparing the Utility of Mitochondrial and Nuclear DNA to Adjust for Genetic Ancestry in Association Studies
Mitochondrial genome-wide association studies identify mitochondrial single nucleotide polymorphisms (mtSNPs) that associate with disease or disease-related phenotypes. Most mitochondrial and nuclear genome-wide association studies adjust for genetic ancestry by including principal components derive...
Autores principales: | Miller, Brendan, Arpawong, Thalida E., Jiao, Henry, Kim, Su-Jeong, Yen, Kelvin, Mehta, Hemal H., Wan, Junxiang, Carpten, John C., Cohen, Pinchas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523867/ https://www.ncbi.nlm.nih.gov/pubmed/30987182 http://dx.doi.org/10.3390/cells8040306 |
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