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Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI

Signal recording and stimulation with high spatial and temporal resolution are of increasing interest with the development of implantable brain-computer interfaces (BCIs). However, implantable BCI technology still faces challenges in the biocompatibility and long-term stability of devices after impl...

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Detalles Bibliográficos
Autores principales: Xi, Ye, Ji, Bowen, Guo, Zhejun, Li, Wen, Liu, Jingquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523908/
https://www.ncbi.nlm.nih.gov/pubmed/30979081
http://dx.doi.org/10.3390/mi10040242
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author Xi, Ye
Ji, Bowen
Guo, Zhejun
Li, Wen
Liu, Jingquan
author_facet Xi, Ye
Ji, Bowen
Guo, Zhejun
Li, Wen
Liu, Jingquan
author_sort Xi, Ye
collection PubMed
description Signal recording and stimulation with high spatial and temporal resolution are of increasing interest with the development of implantable brain-computer interfaces (BCIs). However, implantable BCI technology still faces challenges in the biocompatibility and long-term stability of devices after implantation. Due to the cone structure, needle electrodes have advantages in the biocompatibility and stability as nerve recording electrodes. This paper develops the fabrication of Ag needle micro/nano electrodes with a laser-assisted pulling method and modifies the electrode surface by electrochemical oxidation. A significant impedance reduction of the modified Ag/AgCl electrodes compared to the Ag electrodes is demonstrated by the electrochemical impedance spectrum (EIS). Furthermore, the stability of modified Ag/AgCl electrodes is confirmed by cyclic voltammogram (CV) scanning. These findings suggest that these micro/nano electrodes have a great application prospect in neural interfaces.
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spelling pubmed-65239082019-06-03 Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI Xi, Ye Ji, Bowen Guo, Zhejun Li, Wen Liu, Jingquan Micromachines (Basel) Article Signal recording and stimulation with high spatial and temporal resolution are of increasing interest with the development of implantable brain-computer interfaces (BCIs). However, implantable BCI technology still faces challenges in the biocompatibility and long-term stability of devices after implantation. Due to the cone structure, needle electrodes have advantages in the biocompatibility and stability as nerve recording electrodes. This paper develops the fabrication of Ag needle micro/nano electrodes with a laser-assisted pulling method and modifies the electrode surface by electrochemical oxidation. A significant impedance reduction of the modified Ag/AgCl electrodes compared to the Ag electrodes is demonstrated by the electrochemical impedance spectrum (EIS). Furthermore, the stability of modified Ag/AgCl electrodes is confirmed by cyclic voltammogram (CV) scanning. These findings suggest that these micro/nano electrodes have a great application prospect in neural interfaces. MDPI 2019-04-11 /pmc/articles/PMC6523908/ /pubmed/30979081 http://dx.doi.org/10.3390/mi10040242 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Xi, Ye
Ji, Bowen
Guo, Zhejun
Li, Wen
Liu, Jingquan
Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI
title Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI
title_full Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI
title_fullStr Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI
title_full_unstemmed Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI
title_short Fabrication and Characterization of Micro-Nano Electrodes for Implantable BCI
title_sort fabrication and characterization of micro-nano electrodes for implantable bci
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523908/
https://www.ncbi.nlm.nih.gov/pubmed/30979081
http://dx.doi.org/10.3390/mi10040242
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