Effect of the Phosphodiesterase 5 Inhibitor Sildenafil on Ischemia-Reperfusion-Induced Muscle Mitochondrial Dysfunction and Oxidative Stress

Lower-limb ischemia-reperfusion (IR) is frequent and associated with significant morbidity and mortality. Phosphodiesterase 5 inhibitors demonstrated antioxidant and beneficial effects in several organs submitted to IR, but their effects on muscle mitochondrial functions after lower-limb IR are unkn...

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Detalles Bibliográficos
Autores principales: Tetsi, Liliane, Charles, Anne-Laure, Georg, Isabelle, Goupilleau, Fabienne, Lejay, Anne, Talha, Samy, Maumy-Bertrand, Myriam, Lugnier, Claire, Geny, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523910/
https://www.ncbi.nlm.nih.gov/pubmed/30959961
http://dx.doi.org/10.3390/antiox8040093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523910/
https://www.ncbi.nlm.nih.gov/pubmed/30959961
http://dx.doi.org/10.3390/antiox8040093

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