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Effect of the Phosphodiesterase 5 Inhibitor Sildenafil on Ischemia-Reperfusion-Induced Muscle Mitochondrial Dysfunction and Oxidative Stress
Lower-limb ischemia-reperfusion (IR) is frequent and associated with significant morbidity and mortality. Phosphodiesterase 5 inhibitors demonstrated antioxidant and beneficial effects in several organs submitted to IR, but their effects on muscle mitochondrial functions after lower-limb IR are unkn...
Autores principales: | Tetsi, Liliane, Charles, Anne-Laure, Georg, Isabelle, Goupilleau, Fabienne, Lejay, Anne, Talha, Samy, Maumy-Bertrand, Myriam, Lugnier, Claire, Geny, Bernard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523910/ https://www.ncbi.nlm.nih.gov/pubmed/30959961 http://dx.doi.org/10.3390/antiox8040093 |
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