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Structural Stabilization of Human Transthyretin by Centella asiatica (L.) Urban Extract: Implications for TTR Amyloidosis

Transthyretin is responsible for a series of highly progressive, degenerative, debilitating, and incurable protein misfolding disorders known as transthyretin (TTR) amyloidosis. Since dissociation of the homotetrameric protein to its monomers is crucial in its amyloidogenesis, stabilizing the native...

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Detalles Bibliográficos
Autores principales:	Eze, Fredrick Nwude, Leelawatwattana, Ladda, Prapunpoj, Porntip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523946/ https://www.ncbi.nlm.nih.gov/pubmed/30934952 http://dx.doi.org/10.3390/biom9040128

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