Cargando…

Transcriptomic Response to 1,25-Dihydroxyvitamin D in Human Fibroblasts with or without a Functional Vitamin D Receptor (VDR): Novel Target Genes and Insights into VDR Basal Transcriptional Activity

The vitamin D receptor (VDR) mediates vitamin D actions beyond bone health. While VDR activation by 1,25-dihydroxyvitamin D (1,25D) leads to robust transcriptional regulation, less is known about VDR actions in the absence of 1,25D. We analyzed the transcriptomic response to 1,25D in fibroblasts bea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Costa, Pedro L. F., França, Monica M., Katayama, Maria L., Carneiro, Eduardo T., Martin, Regina M., Folgueira, Maria A. K., Latronico, Ana C., Ferraz-de-Souza, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523947/ https://www.ncbi.nlm.nih.gov/pubmed/30959822 http://dx.doi.org/10.3390/cells8040318

Ejemplares similares

Kidney disease and vitamin D levels: 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, and VDR activation
por: Dusso, Adriana S
Publicado: (2011)

Hereditary 1,25-dihydroxyvitamin D-resistant rickets (HVDRR) caused by a VDR mutation: A novel mechanism of dominant inheritance
por: Isojima, Tsuyoshi, et al.
Publicado: (2015)

1,25‐Dihydroxyvitamin D protects against age‐related osteoporosis by a novel VDR‐Ezh2‐p16 signal axis
por: Yang, Renlei, et al.
Publicado: (2019)

Quercetin Directly Interacts with Vitamin D Receptor (VDR): Structural Implication of VDR Activation by Quercetin
por: Lee, Ki-Young, et al.
Publicado: (2016)

Vitamin D and VDR in cancer cachexia and muscle regeneration
por: Camperi, Andrea, et al.
Publicado: (2017)

Immunohistochemical evaluation of vitamin D receptor (VDR) expression in cutaneous melanoma tissues and four VDR gene polymorphisms
por: La Marra, Francesco, et al.
Publicado: (2017)

1,25-Dihydroxyvitamin D(3) Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPARγ Signaling Pathway
por: Zhang, Xiaoliang, et al.
Publicado: (2015)

The Association Between Vitamin D and Multiple Sclerosis Risk: 1,25(OH)(2)D(3) Induces Super-Enhancers Bound by VDR
por: Lu, Ming, et al.
Publicado: (2019)

Vitamin D, Vitamin D-Binding Proteins, and VDR Polymorphisms in Individuals with Hyperglycaemia
por: Erasmus, Rajiv, et al.
Publicado: (2022)

Vitamin D and VDR in Gynecological Cancers—A Systematic Review
por: Deuster, Eileen, et al.
Publicado: (2017)

Vitamin D inhibits lymphangiogenesis through VDR-dependent mechanisms
por: Yazdani, Saleh, et al.
Publicado: (2017)

Nuclear hormone 1α,25-dihydroxyvitamin D(3) elicits a genome-wide shift in the locations of VDR chromatin occupancy
por: Heikkinen, Sami, et al.
Publicado: (2011)

The relationship of 1,25-dihydroxyvitamin D and Vitamin D binding protein in periodontitis
por: Rafique, Sara, et al.
Publicado: (2019)

Vitamin D receptor (VDR) contributes to the development of hypercalciuria by sensitizing VDR target genes to vitamin D in a genetic hypercalciuric stone-forming (GHS) rat model
por: Guo, Shang, et al.
Publicado: (2020)

Age, serum 25-hydroxyvitamin D and vitamin D receptor (VDR) expression and function in peripheral blood mononuclear cells
por: Coleman, Laura A., et al.
Publicado: (2016)

E-Pharmacophore mapping and docking studies on Vitamin D receptor (VDR)
por: Nagamani, Selvaraman, et al.
Publicado: (2012)

Vitamin D Receptor (VDR) gene polymorphism and risk of ischemic stroke
por: Prabhakar, Puttachandra, et al.
Publicado: (2014)

Crosstalk between Vitamin D Metabolism, VDR Signalling, and Innate Immunity
por: Lin, Rui
Publicado: (2016)

Overexpression of the vitamin D receptor (VDR) induces skeletal muscle hypertrophy
por: Bass, Joseph J., et al.
Publicado: (2020)

Vitamin D Receptor (VDR) Gene Polymorphism in Patients Diagnosed with Colorectal Cancer
por: Latacz, Maria, et al.
Publicado: (2021)

Prognostic significance of vitamin D receptor (VDR) gene polymorphisms in liver cirrhosis
por: Triantos, Christos, et al.
Publicado: (2018)

The Vitamin D Receptor (VDR) Is Expressed in Skeletal Muscle of Male Mice and Modulates 25-Hydroxyvitamin D (25OHD) Uptake in Myofibers
por: Girgis, Christian M., et al.
Publicado: (2014)

Transcriptional effects of 1,25 dihydroxyvitamin D(3) physiological and supra-physiological concentrations in breast cancer organotypic culture
por: Milani, Cintia, et al.
Publicado: (2013)

The Vitamin D Receptor (VDR) Gene Polymorphisms in Turkish Brain Cancer Patients
por: Toptaş, Bahar, et al.
Publicado: (2013)

Vitamin D and VDR Gene Polymorphisms’ Association with Rheumatoid Arthritis in Lithuanian Population
por: Punceviciene, Egle, et al.
Publicado: (2021)

Prevention of Hypomineralization In Auditory Ossicles of Vitamin D Receptor (Vdr) Deficient Mice
por: Delsmann, Maximilian M., et al.
Publicado: (2022)

Vitamin D(3) eradicates Helicobacter pylori by inducing VDR-CAMP signaling
por: Zhang, Ye, et al.
Publicado: (2022)

Vitamin D Receptor (VDR) Genetic Variants: Relationship of FokI Genotypes with VDR Expression and Clinical Disease Activity in Systemic Lupus Erythematosus Patients
por: Meza-Meza, Mónica R., et al.
Publicado: (2022)

Women with recurrent spontaneous abortion have decreased 25(OH) vitamin D and VDR at the fetal-maternal interface
por: Li, N., et al.
Publicado: (2017)

Association of the polymorphism of the vitamin D receptor gene (VDR) with the risk of leprosy in the Brazilian Amazon
por: Paz, Jasna Letícia Pinto, et al.
Publicado: (2021)

Familial vitamin D resistant rickets: End-organ resistance to 1,25-dihydroxyvitamin D
por: Choudhury, Sangita, et al.
Publicado: (2013)

Vitamin D receptor (VDR) on the cell membrane of mouse macrophages participates in the formation of lipopolysaccharide tolerance: mVDR is related to the effect of artesunate to reverse LPS tolerance
por: Zhang, Yu, et al.
Publicado: (2023)

VDR and gemini ligands
por: Laverny, Gilles, et al.
Publicado: (2015)

The c-Raf modulator RRD-251 enhances nuclear c-Raf/GSK-3/VDR axis signaling and augments 1,25-dihydroxyvitamin D3-induced differentiation of HL-60 myeloblastic leukemia cells
por: Supnick, Harrison T., et al.
Publicado: (2018)

Polymorphisms in the Vitamin D Receptor (VDR) and the Risk of Ovarian Cancer: A Meta-Analysis
por: Liu, Yanling, et al.
Publicado: (2013)

Vitamin D Receptor (VDR) Polymorphisms and Late-Onset Alzheimer’s Disease: An Association Study
por: Khorram Khorshid, Hamid Reza, et al.
Publicado: (2013)

Vitamin D Status and Association of VDR Genetic Polymorphism to Risk of Breast Cancer in Ethiopia
por: Ahmed, Jemal Hussien, et al.
Publicado: (2019)

Vitamin D/VDR Protects Against Diabetic Kidney Disease by Restoring Podocytes Autophagy
por: Song, Zhixia, et al.
Publicado: (2021)

Vitamin D receptor (VDR) expression in different molecular subtypes of canine mammary carcinoma
por: Sánchez-Céspedes, R., et al.
Publicado: (2021)

Assessment of Polymorphism of the VDR Gene and Serum Vitamin D Values in Gestational Diabetes Mellitus
por: Siqueira, Thais Walverde, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j23v4836cuomokksh8g7ft3or5