Molecular pattern of lncRNAs in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and progression of this disease remain poorly understood. Over the past decade, many studies have demonstrated the important regulatory roles of long...

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Autores principales: Mai, Haoming, Zhou, Bin, Liu, Li, Yang, Fu, Conran, Carly, Ji, Yuan, Hou, Jinlin, Jiang, Deke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524221/
https://www.ncbi.nlm.nih.gov/pubmed/31097003
http://dx.doi.org/10.1186/s13046-019-1213-0
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author Mai, Haoming
Zhou, Bin
Liu, Li
Yang, Fu
Conran, Carly
Ji, Yuan
Hou, Jinlin
Jiang, Deke
author_facet Mai, Haoming
Zhou, Bin
Liu, Li
Yang, Fu
Conran, Carly
Ji, Yuan
Hou, Jinlin
Jiang, Deke
author_sort Mai, Haoming
collection PubMed
description Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and progression of this disease remain poorly understood. Over the past decade, many studies have demonstrated the important regulatory roles of long non-coding RNAs (lncRNAs) in HCC. Here, we comprehensively review recent discoveries regarding HCC-associated lncRNA functions, which we have classified and described according to their mechanism models. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13046-019-1213-0) contains supplementary material, which is available to authorized users.
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spelling pubmed-65242212019-05-24 Molecular pattern of lncRNAs in hepatocellular carcinoma Mai, Haoming Zhou, Bin Liu, Li Yang, Fu Conran, Carly Ji, Yuan Hou, Jinlin Jiang, Deke J Exp Clin Cancer Res Review Hepatocellular carcinoma (HCC) is one of the most notable lethal malignancies worldwide. However, the molecular mechanisms involved in the initiation and progression of this disease remain poorly understood. Over the past decade, many studies have demonstrated the important regulatory roles of long non-coding RNAs (lncRNAs) in HCC. Here, we comprehensively review recent discoveries regarding HCC-associated lncRNA functions, which we have classified and described according to their mechanism models. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13046-019-1213-0) contains supplementary material, which is available to authorized users. BioMed Central 2019-05-16 /pmc/articles/PMC6524221/ /pubmed/31097003 http://dx.doi.org/10.1186/s13046-019-1213-0 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Mai, Haoming
Zhou, Bin
Liu, Li
Yang, Fu
Conran, Carly
Ji, Yuan
Hou, Jinlin
Jiang, Deke
Molecular pattern of lncRNAs in hepatocellular carcinoma
title Molecular pattern of lncRNAs in hepatocellular carcinoma
title_full Molecular pattern of lncRNAs in hepatocellular carcinoma
title_fullStr Molecular pattern of lncRNAs in hepatocellular carcinoma
title_full_unstemmed Molecular pattern of lncRNAs in hepatocellular carcinoma
title_short Molecular pattern of lncRNAs in hepatocellular carcinoma
title_sort molecular pattern of lncrnas in hepatocellular carcinoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524221/
https://www.ncbi.nlm.nih.gov/pubmed/31097003
http://dx.doi.org/10.1186/s13046-019-1213-0
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