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Aedes aegypti saliva impairs M1-associated proinflammatory phenotype without promoting or affecting M2 polarization of murine macrophages

BACKGROUND: During the feeding process, the mouthparts of hematophagous mosquitoes break the skin barrier and probe the host tissue to find the blood. The saliva inoculated in this microenvironment modulates host hemostasis, inflammation and adaptive immune responses. However, the mechanisms involve...

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Detalles Bibliográficos
Autores principales: Barros, Michele S., Lara, Priscila G., Fonseca, Monique T., Moretti, Eduardo H., Filgueiras, Luciano R., Martins, Joilson O., Capurro, Margareth L., Steiner, Alexandre A., Sá-Nunes, Anderson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524299/
https://www.ncbi.nlm.nih.gov/pubmed/31097013
http://dx.doi.org/10.1186/s13071-019-3487-7