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Pleiotropic Meta-Analysis of Age-Related Phenotypes Addressing Evolutionary Uncertainty in Their Molecular Mechanisms
Age-related phenotypes are characterized by genetic heterogeneity attributed to an uncertain role of evolution in establishing their molecular mechanisms. Here, we performed univariate and pleiotropic meta-analyses of 24 age-related phenotypes dealing with such evolutionary uncertainty and leveragin...
Autores principales: | Kulminski, Alexander M., Loika, Yury, Huang, Jian, Arbeev, Konstantin G., Bagley, Olivia, Ukraintseva, Svetlana, Yashin, Anatoliy I., Culminskaya, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524409/ https://www.ncbi.nlm.nih.gov/pubmed/31134135 http://dx.doi.org/10.3389/fgene.2019.00433 |
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