Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin

Mutations in the RHO gene encoding for the visual pigment protein, rhodopsin, are among the most common cause of autosomal dominant retinitis pigmentosa (ADRP). Previous studies of ADRP mutations in different domains of rhodopsin have indicated that changes that lead to more instability in rhodopsin...

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Detalles Bibliográficos
Autores principales: Mitchell, James, Balem, Fernanda, Tirupula, Kalyan, Man, David, Dhiman, Harpreet Kaur, Yanamala, Naveena, Ollesch, Julian, Planas-Iglesias, Joan, Jennings, Barbara J., Gerwert, Klaus, Iannaccone, Alessandro, Klein-Seetharaman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524802/
https://www.ncbi.nlm.nih.gov/pubmed/31100078
http://dx.doi.org/10.1371/journal.pone.0214639

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