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Alternative polyadenylation of single cells delineates cell types and serves as a prognostic marker in early stage breast cancer

Alternative polyadenylation (APA) in 3’ untranslated regions (3’ UTR) plays an important role in regulating transcript abundance, localization, and interaction with microRNAs. Length-variation of 3’UTRs by APA contributes to efficient proliferation of cancer cells. In this study, we investigated APA...

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Detalles Bibliográficos
Autores principales: Kim, Nayoung, Chung, Woosung, Eum, Hye Hyeon, Lee, Hae-Ock, Park, Woong-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524824/
https://www.ncbi.nlm.nih.gov/pubmed/31100099
http://dx.doi.org/10.1371/journal.pone.0217196