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Induction of Diabetes Abolishes the Antithrombotic Effect of Clopidogrel in Apolipoprotein E–Deficient Mice

Patients with acute coronary syndrome with diabetes mellitus (DM) exhibit an impaired platelet inhibitory response to clopidogrel which is only partially understood. DM was induced by the administration of streptozotocin (STZ) to 9-week-old mice. The antithrombotic effects of clopidogrel (10 mg/kg/d...

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Detalles Bibliográficos
Autores principales:	Sugidachi, A., Ohno, K., Jakubowski, J. A., Ito, Y., Tomizawa, A., Mizuno, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Georg Thieme Verlag KG 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524843/ https://www.ncbi.nlm.nih.gov/pubmed/31249914 http://dx.doi.org/10.1055/s-0037-1605361

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