Orphan Three-Finger Toxins Bind at Tissue Factor–Factor VIIa Interface to Inhibit Factor X Activation: Identification of Functional Site by Docking

Three-finger toxins (3FTxs) contribute to toxicity of venomous snakes belonging to the family Elapidae. Currently, functions of a considerable proportion of 3FTxs are still unknown. Here, we describe the function of orphan group I 3FTxs consisting of four members. We also identified a new member of...

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Detalles Bibliográficos
Autores principales: Choudhury, Manisha, McCleary, Ryan J. R., Kini, R. Manjunatha, Velmurugan, Devadasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524886/
https://www.ncbi.nlm.nih.gov/pubmed/31249954
http://dx.doi.org/10.1055/s-0038-1672184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524886/
https://www.ncbi.nlm.nih.gov/pubmed/31249954
http://dx.doi.org/10.1055/s-0038-1672184

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