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Orphan Three-Finger Toxins Bind at Tissue Factor–Factor VIIa Interface to Inhibit Factor X Activation: Identification of Functional Site by Docking
Three-finger toxins (3FTxs) contribute to toxicity of venomous snakes belonging to the family Elapidae. Currently, functions of a considerable proportion of 3FTxs are still unknown. Here, we describe the function of orphan group I 3FTxs consisting of four members. We also identified a new member of...
Autores principales: | Choudhury, Manisha, McCleary, Ryan J. R., Kini, R. Manjunatha, Velmurugan, Devadasan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524886/ https://www.ncbi.nlm.nih.gov/pubmed/31249954 http://dx.doi.org/10.1055/s-0038-1672184 |
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